Main Information

Target

WIT1

Host Species

Rabbit

Reactivity

Human

Applications

WB, IHC, IF, ELISA

MW

10kD (Calculated)

Conjugate/Modification

Unmodified

Detailed Information

Recommended Dilution Ratio

WB 1:500-1:2000; IHC 1:100-1:300; ELISA 1:10000; IF 1:50-200

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Specificity

This antibody detects endogenous levels of human WIT1

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-15°C to -25°C/1 year(Do not lower than -25°C)

Concentration

1 mg/ml

MW(Calculated)

10kD

Modification

Unmodified

Clonality

Polyclonal

Isotype

IgG

Antigen&Target Information

Immunogen:

Synthesized peptide derived from human WIT1 AA range: 20-100

Specificity:

This antibody detects endogenous levels of human WIT1

Gene Name:

WT1-AS WIT1

Protein Name:

WIT1

Other Name:

Putative Wilms tumor upstream neighbor 1 gene protein ;
WIT-1 ;
Wilms tumor-associated antisense RNA ;

Database Link:

Organism	Gene ID	SwissProt
Human		Q06250;

Background:

This gene is located upstream of the Wilms tumor 1 (WT1) gene; these two genes are bi-directionally transcribed from the same promoter region. This gene is imprinted in kidney, with preferential expression from the paternal allele. Imprinting defects at chromosome 11p13 may contribute to tumorigenesis. [provided by RefSeq, May 2014],

Function:

cell proliferation,

Tissue Expression:

Kidney,Placenta,Uterus,