Tetanus toxin Rabbit Polyclonal Antibody (QYA10777)

产品名称：破伤风毒素兔多克隆抗体

货号：QYA10777

 

主要参数

应用：WB

适应物种：Tetanus toxin

同种型：IgG

储存温度：-20℃

建议工作浓度：WB:1:2000-5000

特异性：抗体可以检测内源性和重组破伤风毒素蛋白

 

背景

破伤风毒素通过抑制神经递质释放发挥作用。它结合外周神经元突触，经内化后通过逆向运输沿轴突进入脊髓，并可在突触后与突触前神经元之间转移。该毒素通过锌内肽酶活性催化突触短蛋白-2（synaptobrevin-2）第76位谷氨酰胺与第77位苯丙氨酸之间的键水解，从而抑制神经递质释放。

 

 

注：本产品仅用于科研用途，不用于诊断和治疗。

Product name: Tetanus toxin Rabbit Polyclonal Antibody

Cat: QYA10777

 

Main parameter

Applications: WB

Reactivity: Tetanus toxin

Isotype: IgG

Storage: -20℃

Recommended dilutions: WB:1:2000-5000

Specificity: Antibody can detects endogenous and recombinant Tetanus toxin protein.

 

Background

Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-|-Phe-77' bond of synaptobrevin-2. 

 

 

P.s. This product is only used for scientific research, not for diagnosis and treatment.