Main Information

Target

COX6B2

Host Species

Rabbit

Reactivity

Human, Rat, Mouse,

Applications

IHC, ELISA

Conjugate/Modification

Unmodified

Detailed Information

Recommended Dilution Ratio

IHC 1:50-200; ELISA(peptide)1:5000-20000

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Specificity

This antibody detects endogenous levels of human COX6B2

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-15°C to -25°C/1 year(Do not lower than -25°C)

Concentration

1 mg/ml

Modification

Unmodified

Clonality

Polyclonal

Isotype

IgG

Antigen&Target Information

Immunogen:

Synthesized peptide derived from human COX6B2 AA range: 40-120

Specificity:

This antibody detects endogenous levels of human COX6B2

Gene Name:

COX6B2

Protein Name:

COX6B2

Other Name:

Cytochrome c oxidase subunit 6B2 ;
Cancer/testis antigen 59 ;
CT59 ;
Cytochrome c oxidase subunit VIb isoform 2 ;
COX VIb-2 ;
Cytochrome c oxidase subunit VIb, testis-specific isoform ;

Database Link:

Organism	Gene ID	SwissProt
Human	125965;	Q6YFQ2;

Background:

function:Connects the two COX monomers into the physiological dimeric form.,similarity:Belongs to the cytochrome c oxidase subunit 6B family.,tissue specificity:Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines.,

Function:

Function:Connects the two COX monomers into the physiological dimeric form.,similarity:Belongs to the cytochrome c oxidase subunit 6B family.,tissue specificity:Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines.,

Cellular Localization:

Mitochondrion inner membrane ; Peripheral membrane protein ; Intermembrane side .

Tissue Expression:

Testis specific. Weak expression in thymus and heart. Expressed in cancer cell lines.

Research Areas:

>>Oxidative phosphorylation ;
>>Metabolic pathways ;
>>Cardiac muscle contraction ;
>>Thermogenesis ;
>>Non-alcoholic fatty liver disease ;
>>Alzheimer disease ;
>>Parkinson disease ;
>>Amyotrophic lateral sclerosis ;
>>Huntington disease ;
>>Prion disease ;
>>Pathways of neurodegeneration - multiple diseases ;
>>Chemical carcinogenesis - reactive oxygen species ;
>>Diabetic cardiomyopathy