Main Information

Target

PKIG

Host Species

Rabbit

Reactivity

Human, Mouse

Applications

IHC, ELISA

Conjugate/Modification

Unmodified

Detailed Information

Recommended Dilution Ratio

IHC 1:50-200; ELISA(peptide)1:5000-20000

Formulation

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Specificity

This antibody detects endogenous levels of human PKIG

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-15°C to -25°C/1 year(Do not lower than -25°C)

Concentration

1 mg/ml

Modification

Unmodified

Clonality

Polyclonal

Isotype

IgG

Antigen&Target Information

Immunogen:

Synthesized peptide derived from human PKIG AA range: 1-80

Specificity:

This antibody detects endogenous levels of human PKIG

Gene Name:

PKIG

Protein Name:

PKIG

Other Name:

cAMP-dependent protein kinase inhibitor gamma ;
PKI-gamma ;

Database Link:

Organism	Gene ID	SwissProt
Human	11142;	Q9Y2B9;

Background:

This gene encodes a member of the protein kinase inhibitor family. Studies of a similar protein in mice suggest that this protein acts as a potent competitive cAMP-dependent protein kinase inhibitor, and is a predominant form of inhibitor in various tissues. The encoded protein may be involved in osteogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

Function:

Function:Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.,similarity:Belongs to the PKI family.,tissue specificity:Ubiquitous.,

Cellular Localization:

nucleus,cytoplasm,

Tissue Expression:

Ubiquitous.