Main Information

Target

EFHD1

Host Species

Rabbit

Reactivity

Human

Applications

WB

MW

27kD (Observed)

Conjugate/Modification

Unmodified

Detailed Information

Recommended Dilution Ratio

WB 1:1000

Formulation

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Specificity

The antibody detects endogenous EFHD1 proteins.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-15°C to -25°C/1 year(Do not lower than -25°C)

MW(Observed)

27kD

Modification

Unmodified

Clonality

Polyclonal

Isotype

IgG

Antigen&Target Information

Immunogen:

Recombinant Protein of EF-hand domain-containing protein D1

Specificity:

The antibody detects endogenous EFHD1 proteins.

Gene Name:

EFHD1

Protein Name:

EF-hand domain-containing protein D1

Other Name:

EF-hand domain-containing protein D1 ;
EF-hand domain-containing protein 1 ;
Swiprosin-2 ;

Database Link:

Organism	Gene ID	SwissProt
Human	80303;	Q9BUP0;
Mouse	98363;	Q9D4J1;

Background:

This gene encodes a member of the EF-hand super family of calcium binding proteins, which are involved in a variety of cellular processes including mitosis, synaptic transmission, and cytoskeletal rearrangement. The protein encoded by this gene is composed of an N-terminal disordered region, proline-rich elements, two EF-hands, and a C-terminal coiled-coil domain. This protein has been shown to associate with the mitochondrial inner membrane, and in HeLa cells, acts as a novel mitochondrial calcium ion sensor for mitochondrial flash activation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016],

Function:

similarity:Contains 2 EF-hand domains.,

Cellular Localization:

Mitochondrion inner membrane .

Tissue Expression:

Brain,Eye,Heart,Hippocampus,Lung,Normal aorta,Placenta,