Recommended Dilution Ratio
WB 1:2000-5000; IHC 1:200-500; IF 1:50-200
Formulation
PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.
Specificity
The antibody detects endogenous Mas1 protein.
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Storage
-15°C to -25°C/1 year(Do not lower than -25°C)
Immunogen:
Synthetic Peptide of Mas1
Specificity:
The antibody detects endogenous Mas1 protein.
Protein Name:
Proto-oncogene Mas
Other Name:
MAS1 ;
MAS ;
Proto-oncogene Mas
Background:
This gene encodes a class I seven-transmembrane G-protein-coupled receptor. The encoded protein is a receptor for angiotensin-(1-7) and preferentially couples to the Gq protein, activating the phospholipase C signaling pathway. The encoded protein may play a role in multiple processes including hypotension, smooth muscle relaxation and cardioprotection by mediating the effects of angiotensin-(1-7). [provided by RefSeq, May 2012],
Function:
Caution:Was originally (PubMed:3419518) thought to be a receptor for angiotensin II.,Disease:The MAS oncogene has a weak focus-inducing activity in transfected NIH 3T3 cells.,similarity:Belongs to the G-protein coupled receptor 1 family.,
Cellular Localization:
Cell membrane ; Multi-pass membrane protein .
Research Areas:
>>Neuroactive ligand-receptor interaction ;
>>Renin-angiotensin system ;
>>Coronavirus disease - COVID-19
