Main Information

Target

TLR13

Host Species

Rabbit

Reactivity

Human, Mouse, Rat

Applications

IHC, IF

Conjugate/Modification

Unmodified

Detailed Information

Recommended Dilution Ratio

IHC 1:200-500; IF 1:50-200

Formulation

PBS, pH 7.4, containing 0.5%BSA, 0.02% sodium azide as Preservative and 50% Glycerol.

Specificity

The antibody detects endogenous TLR13 protein.

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Storage

-15°C to -25°C/1 year(Do not lower than -25°C)

Modification

Unmodified

Clonality

Polyclonal

Isotype

IgG

Antigen&Target Information

Immunogen:

Recombinant Protein of TLR13

Specificity:

The antibody detects endogenous TLR13 protein.

Gene Name:

TLR13

Protein Name:

Toll-like receptor 13

Other Name:

YM3389

Database Link:

Organism	Gene ID	SwissProt
Mouse	279572;	Q6R5N8;

Background:

The TLRs form a family of ligand-binding proteins that engage a variety of microbial products, that on binding, activate signaling cascades leading to the synthesis of proinflammatory molecules. TLR13 is found in mouse and participates in the innate immune response to microbial agents. It acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response.